منابع مشابه
Advances in systems immunology and cancer
The last two decades have generated numerous studies that show the close link between immune response and cancer progression in the mammalian system. In parallel, we have also witnessed significant progress in systemic approaches, such as high-throughput, multi-dimensional and dynamical analyses, in tackling biological complexities. We took this opportunity to organize a research topic that enc...
متن کاملCancer Immunology and Cancer Immunodiagnosis
1 Cancer Autoimmunity Research Laboratory, Department of Biological Sciences, University of Texas, El Paso, TX 79968, USA 2Department of Medical Oncology, The First Affiliated Hospital of Xi’an Jiao Tong University Medical Center, Shaanxi 710061, China 3Division of Hematology/Oncology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA 4Biotherapy Center and Department ...
متن کاملA Quantitative Systems Pharmacology Perspective on Cancer Immunology
The return on investment within the pharmaceutical industry has exhibited an exponential decline over the last several decades. Contemporary analysis suggests that the rate-limiting step associated with the drug discovery and development process is our limited understanding of the disease pathophysiology in humans that is targeted by a drug. Similar to other industries, mechanistic modeling and...
متن کاملCancer Immunology and Immunotherapy
The study of molecular and cellular interplays between immune system and cancerous cells is gaining tremendous momentum across the globe. Concomitantly, with the better insight into the intricacies of cancer immunology, immunotherapeutic approaches to deal with cancer have garnered tremendous boost in the recent past; reckoning with these, it is timely to analyse their potentialities either as ...
متن کاملHormesis in cancer immunology
We recently reported that tumor-directed antibodies could either stimulate, or inhibit, tumor progression, dependent upon the dosage used. The narrow range over which this immune response curve (IRC) occurs is surprising. Here we discuss features of the IRC, the mechanisms identified so far, and the potential clinical implications.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: eLife
سال: 2020
ISSN: 2050-084X
DOI: 10.7554/elife.53839